Description
Product Characteristics:
This protein phosphatase specifically mediates the dephosphorylation of mitochondrial proteins and consequently plays a central role in ATP production. It probably has a preference for proteins phosphorylated on Ser and/or Thr residues compared to phosphorylation on Tyr residues. It is likely to be involved in the regulation of insulin secretion in pancreatic beta cells.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: DUSP23, FLJ46081, MOSP, NB4 apoptosis/dferentiation related protein, Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1, Phosphoinositide lipid phosphatase, PLIP, PNAS 129, protein tyrosine phosphatase mitochondrial 1, Protein-tyrosine phosphatase mitochondrial 1, pten like phosphatase, PTEN-like phosphatase, PTPM1_HUMAN, Ptpmt1.
Target Information: mouse homolog is a phosphatase which specifically catalyzes the conversion of phosphatidylinositol 5-phosphate to phosphatidylinositol [RGD, Feb 2006]