Description
Product Characteristics:
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Subcellular location: Secreted
Synonyms: B2M, Beta-2-MG, beta 2 Microglobulin, Beta 2 microglobulin precursor, beta 2 Microglobulin, Beta chain of mhc class 1 proteins, Hdcma22p, B2MG_HUMAN.
Target Information: This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Sep 2009]