Description
Product Characteristics:
Converts big endothelin-1 to endothelin-1.
Subcellular location: Cell membrane
Synonyms: ECE, Endothelin-converting enzyme 1, ECE-1, ECE1
Target Information: The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Sep 2009]