Description
Product Characteristics:
Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner.Tissue specificity: Abundant in testis, thymus, and in tumor derived cell lines, while barely detectable in liver, prostate, and kidney.
Subcellular location: Cytoplasm
Synonyms: Tumor and microtubule associated protein, LB1, se20 10, Tumor associated microtubule associated protein, AI461656, CKAP 2, Ckap2, CKAP2_HUMAN, CTCL tumor antigen se20 10, CTCL tumor antigen se20-10, Cytoskeleton associated protein 2, Cytoskeleton-associated protein 2, DKFZp686L1238, TMAP, Tumor- and microtubule-associated protein.
Target Information: CKAP2 is a cytoskeleton-associated protein involved in mitotic progression (Seki and Fang, 2007 [PubMed 17376772]).[supplied by OMIM, Mar 2008]