Description
Product Characteristics:
Peptidyl-prolyl cis-trans isomerase (PPIL1) is a member of the cyclophilin family of peptidylprolyl isomerases (PPIases). The cyclophilins are a highly conserved, ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV1 virions. Based on similarity to other PPIases, this protein could accelerate the folding of proteins and might catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular location: Nucleus
Synonyms: CGI 124, CGI-124, CGI124, Cyclophilin related gene 1, cyclophilin-related gene 1, cyclophilinrelated gene 1, CYPL1, hCyPX, MGC678, peptidyl-prolyl cis-trans isomerase, Peptidyl-prolyl cis-trans isomerase-like 1, Peptidylprolyl isomerase cyclophilin like 1, peptidylprolyl isomerase cyclophilin-like 1, peptidylprolyl isomerase cyclophilinlike 1, peptidylprolyl isomerase cyclophilinlike1, peptidylprolyl isomerase like 1, PPIase, PPIL1, PPIL1_HUMAN, rotamase, Rotamase PPIL1.
Target Information: This gene is a member of the cyclophilin family of peptidylprolyl isomerases (PPIases). The cyclophilins are a highly conserved, ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. Based on similarity to other PPIases, this protein could accelerate the folding of proteins and might catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. [provided by RefSeq, Jul 2008]