Description
Product Characteristics: Dtx3 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Dtx3 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Dtx3 functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. Synonyms: Polyclonal Dtx3 antibody, Anti-Dtx3 antibody, deltex 3 homolog, Drosophila antibody, Deltex3 antibody, MGC106339 antibody, mg310 antibody.
Target Information: DTX3 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).[supplied by OMIM, Nov 2009]