Description
Product Characteristics:
Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors.
Subcellular location: Cytoplasm, Nucleus
Synonyms: FIST3, Androgen receptor interacting nuclear protein kinase, Androgen receptor-interacting nuclear protein kinase, ANPK, DYRK6, Fas interacting serine/threonine protein kinase, Fas-interacting serine/threonine-protein kinase, FIST, Hipk3, HIPK3_HUMAN, homeodomain interacting protein kinase 3, Homeodomain-interacting protein kinase 3, Homolog of protein kinase YAK1, PKY, RP24 297H17.5, YAK1.
Target Information: binds the zinc finger region of the androgen receptor\, may play a role in regulation of androgen receptor function [RGD, Feb 2006]