Description
Product Characteristics:
Involved in angiogenesis, promotes angiogenic sprouting. May have potent implications in lung endothelial cell-leukocyte interactions.
Subcellular location: Secreted
Synonyms: endocan, Endothelial cell-specific molecule 1, ESM-1, ESM1
Target Information: This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]