Description
Product Characteristics: PLSCR1 may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.PLSCR1 may play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
Target Information: may act as a downstream mediator of immune response in IgE receptor signaling\, may transport phospholipids in the plasma membrane [RGD, Feb 2006]