Description
Product Characteristics:
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Subcellular location: Cytoplasm, Nucleus
Synonyms: BRRN1, CAP-H, Condensin complex subunit 2, Barren homolog protein 1, Chromosome-associated protein H, hCAP-H, Non-SMC condensin I complex subunit H, XCAP-H homolog, NCAPH, BRRN, CAPH, KIAA0074
Target Information: This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. [provided by RefSeq, Jul 2008]