Description
Product Characteristics:
NMT2 catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. several distinct NMTs exist, varying in apparent molecular weight and /or subcellular distribution.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: Glycylpeptide N tetradecanoyltransferase 2, Myristoyl CoA:protein N myristoyltransferase 2, NMT 2, Peptide N myristoyltransferase 2, Type II N myristoyltransferase, NMT2_HUMAN.
Target Information: N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases. [provided by RefSeq, Jul 2008]