Description
Product Characteristics:
Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: Anandamide amidohydrolase 1, Anandamide amidohydrolase, FA2H, FAAH, FAAH-1, FAAH1_HUMAN, Fatty acid 2-hydroxylase, Fatty acid alpha-hydroxylase, Fatty acid amide hydrolase, Fatty-acid amide hydrolase 1, MGC102823, MGC138146, Oleamide hydrolase 1, Oleamide hydrolase.
Target Information: This gene encodes a protein that is responsible for the hydrolysis of a number of primary and secondary fatty acid amides, including the neuromodulatory compounds anandamide and oleamide. [provided by RefSeq, Jul 2008]