Description
Product Characteristics:
The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.
Subcellular location: Secreted, Cell membrane
Synonyms: NTN, NTT, CXC3, CXC3C, SCYD1, ABCD-3, C3Xkine, fractalkine, neurotactin, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Small-inducible cytokine D1, CX3CL1, FKN, A-152E5.2
Target Information: Chemotactic factor. Binds to CX3CR1