Description
Product Characteristics:
LEC (liver expressed cytokine) displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. It also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. Its expression is upregulated by IL10.
Subcellular location: Secreted
Synonyms: C-C mot chemokine 16, chemokine C-C mot ligand 16, CCL16, CKb12, HCC4, IL10 inducible chemokine, ILINCK, LCC1, Liver CC chemokine 1 precursor, Liver expressed chemokine, LMC, Monotactin 1, Mtn1, NCC4, New CC chemokine 4, SCYA16, SCYL4, Small inducible cytokine A16 precursor, Small inducible cytokine subfamily A Cys Cys member 16, Small-inducible cytokine A16. CCL16_HUMAN
Target Information: This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10. [provided by RefSeq, Jul 2008]