Description
Product Characteristics:
ABCE1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. It is alternatively referred to as the RNase L inhibitor as it functions to block the activity of ribonuclease L(referenced from entrez gene).
Subcellular location: Cytoplasm
Synonyms: 2' 5' oligoadenylate binding protein, 2''-5''-oligoadenylate-binding protein, 2'5' oligoadenylate binding protein, ABC 38, ABC38, ABCE 1, ABCE1, ABCE1_HUMAN, ATP binding cassette sub family E OABP member 1, ATP binding cassette sub family E member 1, ATP-binding cassette sub-family E member 1, HuHP 68, HuHP68, OABP, Ribonuclease 4 Inhibitor, Ribonuclease L 2' 5' oligoisoadenylate synthetase dependent inhibitor, Ribonuclease L 2'5' oligoisoadenylate synthetase dependent inhibitor, Ribonuclease L inhibitor, RLI, RNase L Inhibitor, RNASEL1, RNASELI, RNS 4I, RNS4I.
Target Information: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]