Description
Product Characteristics:
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Subcellular location: Secreted
Synonyms: IBP6, Insulin-like growth factor-binding protein 6, IBP-6, IGF-binding protein 6, IGFBP-6, IGFBP6
Target Information: high-affinity IGF binding ptotein with substantially greater affinity for insulin-like growth factor-II (IGF-II) than IGF-I [RGD, Feb 2006]