Description
Product Characteristics:
Transcription factor playing a role in myogenesis through regulation of muscle precursor cells proliferation.
Subcellular location: Nucleus
Synonyms: HUP1, RMS2, PAX7B, Paired box protein Pax-7, PAX7
Target Information: This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]