Description
Product Characteristics:
This gene encodes a member of the "fused gene" family of proteins, which contain N terminus EF hand domains and multiple tandem peptide repeats. The encoded protein contains two EF hand Ca2+ binding domains in its N terminus and two glutamine and threonine rich 60 amino acid repeats in its C terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation.
Subcellular location: Cytoplasm
Synonyms: HSP 58, HSP-58, PDRC1, 53 kDa putative calcium binding protein, 53 kDa squamous epithelial induced stress protein, 58 kDa heat shock protein, C1orf10, Chromosome 1 open reading frame 10, CRNN, DRC1, SEP53, Squamous epithelial heat shock protein 53, Tumor related protein, CRNN_HUMAN, HSP58/Cornulin.
Target Information: Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)