Description
Product Characteristics: Synonyms:
DKFZp686H12203 antibody,GON 10 antibody,HD 1 antibody,HD1 antibody,HDAC 1 antibody,HDAC1 antibody,hdac1: histone deacetylase 1 antibody,HDAC1_HUMAN antibody,Histone deacetylase 1 (HD1) antibody
Target Information: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]