Description
Product Characteristics:
Involved in the RCC1/Ran-GTPase pathway. RRAGA may play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. biquitously expressed with highest levels of expression in skeletal muscle, heart, and brain.
Subcellular location: Cytoplasm, Nucleus, Cell membrane
Synonyms: RRAGB, Adenovirus E3 14.7 kDa-interacting protein 1, FIP1, Rag A, RAg B, RagA, RAGB, Ras related GTP binding protein A, Ras-related GTP binding protein B, RRAGA_HUMAN.
Target Information: binds GTP\, member of the subfamily of Ras-homologous GTP binding proteins [RGD, Feb 2006]