Description
Product Characteristics:
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Subcellular location: Nucleus
Synonyms: EXPAND1, FLJ14868, FLJ22283, HSPC211, Melanoma associated antigen mutated 1, Melanoma ubiquitous mutated protein, MGC131891, MGC163315, MUM 1, MUM-1, MUM1, MUM1_HUMAN, Mutated melanoma associated antigen 1, Mutated melanoma-associated antigen 1, Protein expandere, PWWP domain containing protein MUM1, PWWP domain-containing protein MUM1.
Target Information: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage (By similarity)