Description
Product Characteristics:
TUSC3 belongs to the OST3/OST6 family of proteins and may be involved in N-glycosylation through its association with N-oligosaccharyl transferase. The TUSC3 gene is a candidate tumour supressor.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: M33, N33, MRT7, MRT22, OST3A, D8S1992, Tumor suppressor candidate 3, Magnesium uptake/transporter TUSC3, Protein N33, TUSC3
Target Information: This gene is a candidate tumor suppressor gene. It is located within a homozygously deleted region of a metastatic prostate cancer. The gene is expressed in most nonlymphoid human tissues including prostate, lung, liver, and colon. Expression was also detected in many epithelial tumor cell lines. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]