Description
Product Characteristics:
Insig2 is highly similar to the protein product encoded by gene Insig1. Both Insig1 protein and Insig2 protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: Hypothetical protein INSIG2, INSIG 2, INSIG-2, INSIG 2 membrane protein, INSIG2 membrane protein, Insulin induced gene 2, Insulin induced gene 2 protein, Insulin induced protein 2, MGC26273, INSI2_HUMAN.
Target Information: The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. [provided by RefSeq, Jul 2008]