Description
Product Characteristics:
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. [provided by RefSeq, Sep 2011].
Subcellular location: Cytoplasm, Cell membrane, Extracellular matrix
Synonyms: PLC 2, PLC gamma 2, PLC IV, PLCG2, 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2, EC 3.1.4.11, Phosphoinositide phospholipase C, Phospholipase C gamma 2, Phospholipase C, gamma 2 phosphatidylinositol specic, PLCG2_HUMAN.
Target Information: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. [provided by RefSeq, Sep 2011]