Description
Product Characteristics:
SNX27 is involved in endocytic trafficking. In T lymphocytes it participates in the endocytic recycling pathway. SNX27 recruits PSCDBP and HT4R to early endosomes.
Subcellular location: Cytoplasm
Synonyms: Methamphetamine responsive transcript 1, MGC126871, MGC126873, MGC20471, MRT1, MY014, RP11-98D18.12, Sorting nexin family member 27, KIAA0488, SNX27_HUMAN, Sorting nexin-27.
Target Information: This gene encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein. [provided by RefSeq, Jul 2008]