Description
Product Characteristics:
Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA.Tissue specificity: Ubiquitous. Highly expressed in the adrenal gland and testis. Weekly expressed in prostate, lung and brain.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: 3 keto acyl CoA synthase ELOVL5, 3-keto acyl-CoA synthase Elovl5, dJ483K16.1, Elongation of very long chain fatty acids like 5, Elongation of very long chain fatty acids protein 5, ELOV5_HUMAN, ELOVL 5, ELOVL family member 5, ELOVL family member 5 elongation of long chain fatty acids, ELOVL family member 5, elongation of long chain fatty acids FEN1/Elo2, SUR4/Elo3-like, yeast, ELOVL fatty acid elongase 5, ELOVL2, elovl5, Fatty acid elongase 1, HELO1, Homolog of yeast long chain polyunsaturated fatty acid elongation enzyme 2, OTTHUMP00000017867, RP3 483K16.1.
Target Information: ELOVL5 plays a role in elongation of long-chain polyunsaturated fatty acids (Leonard et al., 2000 [PubMed 10970790]).[supplied by OMIM, Mar 2008]