Description
Product Characteristics: Synonyms:
Component of gems 2 antibody,GEMI2_HUMAN antibody,Gemin-2 antibody,gemin2 antibody,SIP 1antibody,SIP-1 antibody,SIP1 antibody,SIP1 delta antibody,SMN interacting protein 1 antibody,SMNinteracting protein 1 delta antibody,SMN-interacting protein 1 antibody,Survival interacting protein 1antibody,Survival of motor neuron protein interacting protein 1 antibody,Survival of motor neuronprotein-interacting protein 1 antibody
Target Information: The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]