Description
Product Characteristics:
KHK encodes the gene ketohexokinase that catalyzes conversion of fructose to fructose 1 phosphate. The splice variant presented encodes the highly active form found in liver, renal cortex, and small intestine, while the alternate variant encodes the lower activity form found in most other tissues.
Subcellular location: Cytoplasm, Extracellular matrix
Synonyms: fructokinase, Hepatic fructokinase, ketohexokinase, Ketohexokinase isoform a, KHK, EC 2.7.1.3, KHK_HUMAN.
Target Information: This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]