Description
Product Characteristics:
Cytokine that contributes to the inflammatory response in vivo.
Subcellular location: Secreted
Synonyms: TIFa, IL-21, IL-22, ILTIF, IL-TIF, IL-D110, zcyto18, TIFIL-23, Interleukin-22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor, IL22, UNQ3099/PRO10096
Target Information: The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008]