Description
Product Characteristics:
CABLES2 is a proapoptotic factor involved in both p53-mediated and p53-independent apoptotic pathways. ik3-1/CABLES1, a closely related molecule, has been identified to be a candidate tumor suppressor for colon and head/neck cancers.The exact function of this protein is unknown, but it is probably involved in G1-S cell cycle transition. CABLES2 binds to CDK3, CDK5 and ABL1.
Subcellular location: Cytoplasm, Nucleus, Cell membrane
Synonyms: CABLES 2, Cdk5 and Abl enzyme substrate 2, Ik3 2, Interactor with CDK3 2, C20orf150, CABL2_HUMAN.
Target Information: Unknown. Probably involved in G1-S cell cycle transition