Description
Product Characteristics:
May play a role in dendritic cell function and in adaptive immunity.
Subcellular location: Cytoplasm
Synonyms: LAMP, CD208, DCLAMP, LAMP-3, TSC403, DC LAMP, DC-LAMP, Lysosome-associated membrane glycoprotein 3, Lysosomal-associated membrane protein 3, DC-lysosome-associated membrane glycoprotein, Protein TSC403, LAMP3
Target Information: Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).[supplied by OMIM, Dec 2010]