Description
Product Characteristics: The homeodomain-containing transcription factor NKX3A is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3A protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia. Synonyms: Monoclonal POLR2G antibody, Anti-POLR2G antibody, RNA polymerase II subunit B7 antibody, RPB7 antibody, hRPB19 antibody, hsRPB7 antibody, MGC138367 antibody, MGC138369 antibody.
Target Information: This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation. [provided by RefSeq, Jan 2009]