Description
Product Characteristics: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. Synonyms: Monoclonal POLR1D antibody, Anti-POLR1D antibody, Polymerase (RNA) I polypeptide D antibody, RPA9 antibody, RPA16 antibody, RPAC2 antibody, POLR1C antibody, RPO1-3 antibody, MGC9850 antibody, FLJ20616 antibody.
Target Information: The protein encoded by this gene is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011]