Description
Product Characteristics:
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
Subcellular location: Nucleus
Synonyms: H1E, H1.4, H1F4, H1s-4, dJ221C16.5, Histone H1.4, Histone H1b, Histone H1s-4, HIST1H1E
Target Information: facilitates the organization and condensation of polynucleosome filaments into chromatin fibers [RGD, Feb 2006]