Biorbyt's MEIS1 antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The MEIS1 antibody was generated using MEIS1 as the antigen and it reacts with Homo Sapiens, and Human.
Description
Rabbit polyclonal to MEIS1.Homeobox genes play crucial roles in normal development and neoplasia. Myeloid ecotropic viralintegration site 1 homolog (MEIS1) is a homeobox protein belonging to the TALE ('three amino acidloop extension')/MEIS homeobox family. MEIS1 contains a homeobox DNA-binding domain and actsas a transcriptional regulator of PAX6. It also acts as a transcriptional activator of PF4 in complex withPBX1 or PBX2. MEIS1 is required for hematopoiesis, megakaryocyte lineage development andvascular patterning. In addition, MEIS1 may function as a cofactor for HOXA7 and HOXA9 in theinduction of myeloid leukemias