Anti-LAMP1 antibody - Lysosome Marker ab24170 from Abcam

Product Specs
ItemAnti-LAMP1 antibody - Lysosome Marker
CompanyAbcam
Price Pricing Info Supplier Page View Company Product Page
Catalog Numberab24170
Antibody TypePrimary
Quantity100 UG
ClonalityPolyclonal
HostRabbit
IsotypeIgG
ApplicationsImmunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
Conjugate/TagUnconjugated
Concentration1 mg/ml
Research AreaImmuno-oncology
Gene NameLAMP1
TargetLAMP1
ReactivityHuman (Hu)

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

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Website: http://www.abcam.com

(1) A tetracationic porphyrin with dual anti-prion activityiScienceSeptember 15, 2023Antonio Masone, Chiara Zucchelli, Enrico Caruso, Giada Lavigna, Hasier Eraña, Gabriele Giachin, Laura Tapella, Liliana Comerio, Elena Restelli, Ilaria Raimondi, et al.cells were then incubated with anti-PrP mAb 12B2 (WUR; 1:500), rabbit polyclonal anti-LAMP1 (Abcam ab24170; 1:1000), chicken polyclonal anti-MAP2 (Abcam ab5392; 1:50000) primary antibodies diluted in blocking

(2) HMMR alleviates endoplasmic reticulum stress by promoting autophagolysosomal activity during endoplasmic reticulum stress-driven hepatocellular carcinoma progressionCancer communications (London, England)September 1, 2023He L, Li H, Li C, Liu ZK, Lu M, Zhang RY, Wu D, Wei D, Shao J, Liu M, et al.Sigma, Aldrich Chemie, Taufkirchen, Germany), CTSD (1:1000; 21327‐1‐AP, Proteintech), LAMP1 (1:1000; ab24170, Abcam), TFEB (1:1000; 13372‐1‐AP, Proteintech), MITF (1:1000; 13092‐1‐AP, Proteintech), lamin B1 (1:1000;

(3) Reduction of nemo-like kinase increases lysosome biogenesis and ameliorates TDP-43-related neurodegenerationThe Journal of clinical investigationAugust 15, 2023Tejwani L, Jung Y, Kokubu H, Sowmithra S, Ni L, Lee C, Sanders B, Lee PJ, Xiang Y, Luttik K, et al.anti–cathepsin D (Abcam; ab6313; 1:200), goat anti-ChAT (Millipore; AB144P; 1:500), rabbit anti-Lamp1 (Abcam; ab24170; 1:400), chicken anti-GFAP (Abcam; ab4674; 1:2,000), mouse anti-NeuN (Millipore; MAB377; 1:200), mouse

(4) The endosomal system of primary human vascular endothelial cells and albumin-FcRn traffickingJ Cell SciAugust 1, 2023Andreas Pannek, Janine Becker-Gotot, Steven K. Dower, Anne M. Verhagen, Paul A. GleesonGM130 (610823, clone 35/GM130, BD Biosciences; 1:800 for IF); rabbit polyclonal antibodies to LAMP1 (ab24170, Abcam; 1:500 for IF), mCherry (ab183628, Abcam; 1:500 for IF and WB) and vWF (ab6994, Abcam; 1:400

(5) Impaired Lysosome Reformation in Chloroquine-Treated Retinal Pigment Epithelial CellsInvestigative ophthalmology & visual scienceAugust 1, 2023Cardoso MH, Hall MJ, Burgoyne T, Fale P, Storm T, Escrevente C, Antas P, Seabra MC, Futter CE.ARPE19",WB,1:100 ,,,,IF,1:100 ,,,hESC-RPE,IEM,1:100 ,,,hESC-RPE,WB,1:1000 HSc70,Sc-7298,Santa Cruz Biotechnology,pRPE,WB,"1:10,000" LAMP1,Ab24170,Abcam,pRPE,WB,1:150 CD107a,,,,, LAMP1,H4A3,DSHB,ARPE19,IF,1:100 LAMP1 (C54H11),#3243,Cell Signaling,hEScRPE,WB,1:1000 TGN46,PA5-23068,Invitrogen,ARPE19,IF,1:100 RetP1,MA5-11741,Invitrogen,hEScRPE,IF,1:100 P62,sc-28359,Santa Cruz

(6) Apolipoprotein E intersects with amyloid-β within neuronsLife Science AllianceAugust 1, 2023Sabine C Konings, Emma Nyberg, Isak Martinsson, Laura Torres-Garcia, Oxana Klementieva, Claudia Guimas Almeida, Gunnar K Gourasmonoclonal anti-Iba1,Millipore,Cat# MABN92; RRID: AB_10917271 Rabbit polyclonal anti-LAMP1,Abcam,Cat#ab24170; RRID: AB_775978 Rat monoclonal anti-LAMP1,Abcam,Cat# ab25245; RRID: AB_449893 Rabbit polyclonal anti-LC3β,Cell signaling

(7) SARS-CoV-2 ORF3c impairs mitochondrial respiratory metabolism, oxidative stress, and autophagic fluxiScienceJuly 21, 2023Mozzi A, Oldani M, Forcella ME, Vantaggiato C, Cappelletti G, Pontremoli C, Valenti F, Forni D, Saresella M, Biasin M, et al.(2E1/53),Thermo Fisher Scientific,"Cat# MA3-013, RRID:AB_325461" Rabbit polyclonal anti-LAMP1,Abcam,"Cat# ab24170, RRID:AB_775978" Goat polyclonal anti-EEA1 (N-19),Santa Cruz Biotechnology,"Cat# sc-6415, RRID:AB_2096822" Rabbit

(8) Loss of Progranulin Results in Increased Pan-Cathepsin Activity and Reduced LAMP1 Lysosomal ProteinbioRxiv : the preprint server for biologyJuly 16, 2023Anderson A, Tansey MG.Information on the antibodies used can be found in Table 1. Primary antibodies used were LAMP1 (rabbit, Abcam ab24170) diluted 1:1000, PGRN (sheep, R&D AF2557) diluted 1:400 and Cathepsin B (CTS B)(rabbit, Abcam ab214428)

(9) Tolerance of repeated toxic injuries of murine livers is associated with steatosis and inflammationCell Death & DiseaseJuly 12, 2023Seddik Hammad, Christoph Ogris, Amnah Othman, Pia Erdoesi, Wolfgang Schmidt-Heck, Ina Biermayer, Barbara Helm, Yan Gao, Weronika Piorońska, Christian H. Holland, et al.incubated with Bodipy (Life Technologies, D-3922, 1:250), LC3 (Abgent, AP1802a; 1:100), LAMP1 (Abcam, ab24170, 1:100), or PLIN3 (ProSci, 3883, 1:100) for 30 min. After rinsing steps with 60% isopropanol, cryosections

(10) Host Lipid Transport Protein ORP1 Is Necessary for Coxiella burnetii Growth and Vacuole Expansion in MacrophagesmSphereJune 22, 2023Baleigh Schuler, Margaret Sladek, Stacey D. Gilkinstead of staining with anti-CD63 antibody, cells were stained with rabbit anti-LAMP1 antibody (Abcam ab24170), and images were taken using a Leica epifluorescence microscope using a 100× oil objective (1.4 NA). Filipin

(11) A Novel Small NPC1 Promoter Enhances AAV-Mediated Gene Therapy in Mouse Models of Niemann–Pick Type C1 DiseaseCellsJune 13, 2023Michael Paul Hughes, Hemanth Ramesh Nelvagal, Oliver Coombe-Tennant, Dave Smith, Claire Smith, Giulia Massaro, Laura Poupon-Bejuit, Frances Mary Platt, Ahad Abdul RahimMAB3402), microglia (rat anti-mouse CD68, 1:400, Bio-Rad MCA1957), LAMP1 (rabbit anti-LAMP1, 1:200, Abcam ab24170), and calbindin (Rabbit anti-calbindin, 1:2000, Swant CB38a). A total of 20 µm coronal sections were

(12) Replicative Acinetobacter baumannii strains interfere with phagosomal maturation by modulating the vacuolar pHPLOS PathogensJune 9, 2023Jesus S. Distel, Gisela Di Venanzio, Joseph J. Mackel, David A. Rosen, Mario F. Feldmanantibodies produced in rabbit: anti-LC3 (Sigma, L7543), anti-EEA1 (Invitrogen, PA1-063A), anti-LAMP1 (Abcam, ab24170) or anti-A. baumannii at a 1:100 dilution for 1 h at 37 °C. The cells were then washed 3 times with

(13) Endothelial TFEB signaling-mediated autophagic disturbance initiates microglial activation and cognitive dysfunctionAutophagyJune 3, 2023Yaping Lu, Xiang Chen, Xiuxiu Liu, Yi Shi, Zhaocong Wei, Lili Feng, Quan Jiang, Weifeng Ye, Takuya Sasaki, Kohji Fukunaga, et al.(1:5000; Cell Signaling Technology, 5114), anti-TFEB (1:1000; Abcam, ab2636), anti-LAMP1 (1:3000; Abcam, ab24170), anti-LAMP2A (1:3000; Abcam, ab18528), anti-PPP3/calcineurin was prepared as previously described and

(14) Juvenile CLN3 disease is a lysosomal cholesterol storage disorder: similarities with Niemann-Pick type C diseaseEBioMedicineJune 1, 2023Chen J, Soni RK, Xu Y, Simoes S, Liang FX, DeFreitas L, Hwang R Jr, Montesinos J, Lee JH, Area-Gomez E, et al.Fisher. Antibodies The antibodies were obtained from the following sources: rabbit antibodies for LAMP1 [Abcam Cat# ab24170, RRID:AB_775978, 10 μg at 1 mg/mL for immunoprecipitation (IP) and 1/250 for western blot (WB)], Rab5A

(15) The mitophagy receptor BNIP3 is critical for the regulation of metabolic homeostasis and mitochondrial function in the nucleus pulposus cells of the intervertebral discAutophagyJune 1, 2023Madhu V, Hernandez-Meadows M, Boneski PK, Qiu Y, Guntur AR, Kurland IJ, Barve RA, Risbud MV.(Novus Biologicals, NBP1-81,063), anti-LC3 (Cell Signaling Technology, 12,741), and anti-LAMP1 (Abcam, ab24170), in blocking buffer (2% BSA + 0.1% Triton X-100) at 1:100 to 1:200 at 4°C overnight. After washing,

(16) Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathyThe Journal of clinical investigationJune 1, 2023Braun F, Abed A, Sellung D, Rogg M, Woidy M, Eikrem O, Wanner N, Gambardella J, Laufer SD, Haas F, et al.ab96246), and ITM2B (Abcam, ab119044). TOM20 (Santa Cruz Biotechnology, sc-11415) and LAMP1 (Abcam, ab24170) were used for immunofluorescence staining. Immunofluorescence staining was performed on differentiated

(17) The Autophagy Nucleation Factor ATG9 Forms Nanoclusters with the HIV-1 Receptor DC-SIGN and Regulates Early Antiviral Autophagy in Human Dendritic CellsInternational Journal of Molecular SciencesMay 19, 2023Laure Papin, Martin Lehmann, Justine Lagisquet, Ghizlane Maarifi, Véronique Robert-Hebmann, Christophe Mariller, Yann Guerardel, Lucile Espert, Volker Haucke, Fabien P. BlanchetDarmstadt, Germany). Antibodies against ATG16L1 (ab187671), ULK1 (ab128859), ATG9 (ab108338), Lamp1 (ab24170), anti-P62/SQSTM-1 (ab56416) and HA-tag (ab9110) were from Abcam (Cambridge, UK). Anti-LC3 (PM036) and

(18) Obesity impairs cardiolipin-dependent mitophagy and therapeutic intercellular mitochondrial transfer ability of mesenchymal stem cellsCell death & diseaseMay 13, 2023Sagar S, Faizan MI, Chaudhary N, Singh V, Singh P, Gheware A, Sharma K, Azmi I, Singh VP, Kharya G, et al.Anti-EpCAM,Abcam,ab32392 18,Anti-alpha Tubulin,Abcam,ab7291 19,Anti-Mitofusin 1,Abcam,ab57602 20,Anti-LAMP1,Abcam,ab24170 21,Anti-Cytochrome C,Abcam,ab90529 22,Anti-Parkin,Cell Signaling Technology,2132 S 23,Anti-Phospho

(19) Mitofusin 2 Sustains the Axonal Mitochondrial Network to Support Presynaptic Ca2+ Homeostasis and the Synaptic Vesicle Cycle in Rat Hippocampal AxonsThe Journal of NeuroscienceMay 10, 2023Jason D. Vevea, Edwin R. ChapmanSigma-Aldrich,AB10527|Anti-VDAC Antibody; RRID:AB_10806766,IB (1:1000) Antibody,anti-LAMP1 (rabbit polyclonal),Abcam,ab24170; RRID:AB_775978,IB (1:500) Antibody,anti-PSD95 (mouse monoclonal),Thermo Fisher Scientific,Clone 7E3-1B8;

(20) Regulation of Macrophage Cell Surface GAPDH Alters LL-37 Internalization and Downstream Effects in the CellJournal of Innate ImmunityApril 20, 2023Asmita Dhiman, Sharmila Talukdar, Gaurav Kumar Chaubey, Rahul Dilawari, Radheshyam Modanwal, Surbhi Chaudhary, Anil Patidar, Vishant Mahendra Boradia, Pradeep Kumbhar, Chaaya Iyengar Raje, et al.endosomes, and lysosomes were identified using anti-Rab5, Rab7, and LAMP-1 (Abcam #ab13253, ab137029, ab24170) respectively. For analysis of autophagosome machinery components, ATG5 (Cell Signaling Technology #2630S),

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Anti-LAMP1 antibody - Lysosome Marker from Abcam

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Anti-LAMP1 antibody - Lysosome Marker from Abcam

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