The TYR, ID (Tyrosinase, Monophenol Monooxygenase, Tumor Rejection Antigen AB, SK29-AB, LB24-AB) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The TYR, ID (Tyrosinase, Monophenol Monooxygenase, Tumor Rejection Antigen AB, SK29-AB, LB24-AB) Antibody has been validated for the following applications: ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
TYR catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The protein has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this protein result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation