Description
Product Characteristics:
Probable transporter.
Subcellular location: Cell membrane
Synonyms: ABCC 12, Abcc12, ATP binding cassette sub family C CFTR MRP member 12, ATP binding cassette protein C12, ATP binding cassette transporter sub family C member 12, ATP binding cassette, sub family C, member 12, ATP-binding cassette sub-family C member 12, MRP9, MRP9_HUMAN, Multidrug resistance associated protein 9, Multidrug resistance-associated protein 9.
Target Information: This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008]