Description
Product Characteristics:
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP alpha, CEBP delta, and CEBP gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL1 response element in the IL6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
Synonyms: CEBP-beta, CLEBP beta, CCAAT Enhancer Binding Protein beta, AGP/EBP, C EBP beta, C/EBP related protein 2, CEBPB, CRP2, IL 6DBP, IL6DBP, Interleukin 6 dependent binding protein, LAP, Liver enriched transcriptional activator, NF IL6, NFIL6, Nuclear factor NF IL6, SF B, SFB, Silencer factor B, TCF5, Transcription factor 5, CEBPB_RAT.
Target Information: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. [provided by RefSeq, Jul 2008]