Description
Product Characteristics:
KLRF1 is involved in the natural killer mediated cytolysis of PHA-induced lymphoblasts.
Subcellular location: Cell membrane
Synonyms: C type lectin domain family 5 member C, CLEC5C, killer cell lectin like receptor F1, Killer cell lectin like receptor subfamily F member 1, KLRF 1, Lectin like receptor F1, MGC119907, MGC119908, MGC119909, ML, NKp80.
Target Information: KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009]