Description
Product Characteristics:
GNB2 belongs to the WD repeat G protein beta family. Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Subcellular location: Cytoplasm
Synonyms: G protein beta 2 subunit, G protein subunit beta 2, G protein, beta 2 subunit, Gnb2l1, guanine nucleotide binding protein G protein, beta polypeptide 2, Guanine nucleotide binding protein beta 2 subunit, Guanine nucleotide binding protein G I G S G T beta 2 subunit 2, Guanine nucleotide binding protein G protein beta polypeptide 2, guanine nucleotide binding protein, beta 2 subunit, RACK1, Receptor for activated C kinase, Receptor of activated protein kinase C 1, signal transducing guanine nucleotide binding regulatory protein beta, Transducin beta chain 2, OTTHUMP00000174601, OTTHUMP00000174602, GBB2_HUMAN.
Target Information: Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR. [provided by RefSeq, Jul 2008]