Description
Product Characteristics: Function: Receptor-activated non-selective cation channel involved in the nose-touch response and foraging behavior. Contributes to the neural responses of sensory neurons to touch, particularly after repeated mechanical stimulation. Has no apparent role in thermosensory or chemosensory behaviors.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Expressed in many sensory neurons, including OLQ and IL1 neurons.
Miscellaneous: Worms lacking trpa-1 exhibit specific defects in mechanosensory behaviors: abnormal head withdrawal reflex, defective reversal behavior in response to nose-touch and foraging behaviors. Also known as: Transient receptor potential cation channel subfamily A member 1, ankyrin-like withtransmembrane domains protein 1, transformation sensitive protein p120, ANKTM1, trpa-1.
Target Information: The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined\, however, studies indicate the function may involve a role in signal transduction and growth control. [provided by RefSeq, Jul 2008]