Description
Product Characteristics: SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein. Mucolipins constitute a family of cation channel proteins with homologs in mouse, Drosophila, and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV.,Mammalian Mucolipins,Mcoln3, mucolipin 3, Va, TRPML3, TRP-ML3
Target Information: This gene encodes one of members of the mucolipin cation channel proteins. Mutation studies of the highly similar protein in mice have shown that the protein is found in cochlea hair cells, and mutant mice show early-onset hearing loss and balance problems. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]