Description
Product Characteristics: CACNA1C, calcium channel, voltage-dependent, L type, alpha 1C subunit, CACH2, CACN2, CACNL1A1, CCHL1A1, CaV1.2, MGC120730, TS, DHPR, alpha-1 subunit, calcium channel, L type, alpha 1 polypeptide, isoform 1, cardic muscle, calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit, voltage-dependent L-type calcium channel alpha 1C subunit, voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*, voltage-gated calcium channel alpha subunit Cav1.2
Target Information: This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012]