Description
Product Characteristics: This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. MAGP-2 (also known as Microfibril-associated glycoprotein 2, MFAP-2, MP25 and Microfibrillar-associated protein 5 precursor) is a secreted, extracellular matrix protein which is a component of the elastin-associated microfibrils. It forms intermolecular disulfide bonds either with other MAGP-2 molecules or with other components of the microfibrils. MAGP-2 is upregulated in some ovarian cancers and is associated with poor survival of ovarian cancer patients.
Synonyms: MFAP 5 antibody, MFAP5 antibody, Microfibril associated glycoprotein 2 antibody, microfibrillar associated protein 5 antibod
Target Information: This gene encodes a 25-kD microfibril-associated glycoprotein which is rich in serine and threonine residues. It lacks a hydrophobic carboxyl terminus and proline-, glutamine-, and tyrosine-rich regions, which are characteristics of a related 31-kDa microfibril-associated glycoprotein (MFAP2). The close similarity between these two proteins is confined to a central region of 60 aa where precise alignment of 7 cysteine residues occurs. The structural differences suggest that this encoded protein has some functions that are distinct from those of MFAP2. [provided by RefSeq, Jul 2008]