Description
Product Characteristics: NFATC4, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4, NF-ATc4, NFAT3, T cell transcription factor NFAT3, nuclear factor of activated T-cells, cytoplasmic 4
Target Information: The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Oct 2008]