Description
Product Characteristics: FREM2, FRAS1 related extracellular matrix protein 2, DKFZp686J0811, DKFZp781I048, KIAA1074, ECM3 homolog, FRAS1-related extracellular matrix protein 2, OTTHUMP00000018288, OTTHUMP00000018289
Target Information: This gene encodes a membrane protein that belongs to the FRAS1 family. This extracellular matrix protein is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes. Mutations in this gene are associated with Fraser syndrome. [provided by RefSeq, Jul 2008]