Phospho-PLCgamma1 (Tyr783) Antibody 2821S from Cell Signaling Technology

Product Specs
ItemPhospho-PLCgamma1 (Tyr783) Antibody
CompanyCell Signaling Technology
Price Pricing Info Supplier Page View Company Product Page
Catalog Number2821S
Quantity100 µl
ApplicationsW
ReactivityH, M, R
TargetPLCg1 (Tyr783) phosphate
ModificationsPLCg1 (Tyr783) phosphate
HostRabbit
NCBI Gene AliasesNCKAP3, PLC-II, PLC1, PLC148, PLCgamma1
NCBI Full Gene Namephospholipase C gamma 1
ClonalityPolyclonal
Research AreaCa, cAMP and Lipid Signaling
Molecular Weight155

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) PDE4DIP contributes to colorectal cancer growth and chemoresistance through modulation of the NF1/RAS signaling axisCell Death & DiseaseJune 24, 2023Rulu Pan, Juji Dai, Weicheng Liang, Hongxiao Wang, Lin Ye, Siqi Ye, Ziqi Lin, Shishun Huang, Yan Xiong, Li Zhang, et al.(#2276), PCNA (#13110), phospho-MARCKS (#11992), MARCKS (#5607), phospho-PKC (pan) (#2060), phospho-PLCγ (#2821), phospho-PKA (#4781), PKA (#4782), phospho-CREB (#9198), CREB (#9197), GM130 (#12480), IgG-rabbit (#2729),

(2) Structural basis for FGF hormone signallingNatureJune 1, 2023Chen L, Fu L, Sun J, Huang Z, Fang M, Zinkle A, Liu X, Lu J, Pan Z, Wang Y, et al.phosphorylated FRS2α (1:1000, no. 3864S, Cell Signaling Technology), phosphorylated PLCγ1 (1:1000, no. 2821S, Cell Signaling Technology), phosphorylated ERK1/2 (1:1000, no. 4370S, Cell Signaling Technology), α-tubulin

(3) The E2 ubiquitin-conjugating enzymes UBE2D1 and UBE2D2 regulate VEGFR2 dynamics and endothelial functionJournal of cell scienceMay 15, 2023Critchley WR, Smith GA, Zachary IC, Harrison MA, Ponnambalam S.phosphorylated Akt (1:1000 for IB, 4060B), PLCγ1 (1:1000 for IB, #5690), phosphorylated PLCγ1 (1:1000 for IB, #2821), ERK1/2 (1:1000 for IB, #4695) and phosphorylated ERK1/2 (1:1000 for IB, #4370) from Cell Signalling

(4) Activin A Limits VEGF-Induced Permeability via VE-PTPInternational journal of molecular sciencesMay 12, 2023Baccouche B, Lietuvninkas L, Kazlauskas A.CulturewareTM (Applied BioPhysics, Inc., Troy, NY, USA). Anti–Enos Ser1177 (9571), Anti-PLC Tyr783 (2821), Anti-VEGFR2 (247), and Anti-P-VEGFR2 1175 (2478) were purchased from Cell Signaling, Inc. (Danvers,

(5) Thalidomide Attenuates Mast Cell Activation by Upregulating SHP-1 Signaling and Interfering with the Action of CRBNCellsFebruary 1, 2023Hyeun-Wook Chang, Kyeong-Hwa Sim, Youn-Ju Lee(#9102), p-IKK (#2697), p-JNK (#9251), JNK (#9258), p-p38 MAPK (#9215), p38 MAPK (#9212), p-PLCγ1 (#2821), and GAPDH (#2118) were purchased from Cell Signaling Technology (Danvers, MA). Antibodies against

(6) Inherited human ITK deficiency impairs IFN-γ immunity and underlies tuberculosisJournal of Experimental MedicineJanuary 2, 2023Masato Ogishi, Rui Yang, Rémy Rodriguez, Dominic P. Golec, Emmanuel Martin, Quentin Philippot, Jonathan Bohlen, Simon J. Pelham, Andrés Augusto Arias, Taushif Khan, et al.Clone: E4X7M, 1:1,000, 4 °C overnight), anti-phospho-PLCγ1 (Y783) rabbit polyclonal antibody (Cat: 2821, 1:1,000; Cell Signaling Technology, 4 °C overnight), HRP-conjugated anti-DDK mAb (Cat: 637311, Clone:

(7) Kinetic proofreading through the multi-step activation of the ZAP70 kinase underlies early T cell ligand discriminationNature immunologySeptember 1, 2022Voisinne G, Locard-Paulet M, Froment C, Maturin E, Menoita MG, Girard L, Mellado V, Burlet-Schiltz O, Malissen B, Gonzalez de Peredo A, et al.(Cell Signaling Technology, catalog no. 2855, clone 234B4), anti-PLCγ1-pY783 (Cell Signaling Technology, catalog no. 2821), anti-PLCγ1 (Cell Signaling Technology, catalog no. 2822), anti-LAT-pY220 (Cell Signaling Technology,

(8) Effects of 1α,25-dihydroxyvitamin D3 and tacalcitol on cell signaling and anchorage-independent growth in T98G and U251 glioblastoma cellsBiochemistry and Biophysics ReportsSeptember 1, 2022Frida Olsson, Niki Sarri, Natalia Papadopoulos, Johan Lennartsson, Maria Norlinover-night with primary antibodies. The following primary antibodies were used: rabbit anti-pY783-PLCγ1 (#2821, 1:1000, Cell Signaling Technology), mouse anti-PLCγ1 (H00005335-M01, 1:1000, Novus Biologicals), mouse

(9) A Cysteine Residue within the Kinase Domain of Zap70 Regulates Lck Activity and Proximal TCR SignalingCellsSeptember 1, 2022Annika Schultz, Marvin Schnurra, Ali El-Bizri, Nadine M. Woessner, Sara Hartmann, Roland Hartig, Susana Minguet, Burkhart Schraven, Luca Simeoni"Merck Millipore, upstate" Lck,3A5,Santa Cruz Biotechnology Lck pY505,2751S,Cell Signaling Technology PLCγ pY783,2821S,Cell Signaling Technology p44/42 MAPK (Erk1/2) (pT202/pY204),D13.14.4E,Cell Signaling Technology Src

(10) The hexosamine pathway and coat complex II promote malignant adaptation to nutrient scarcityLife science allianceJuly 1, 2022Dragic H, Barthelaix A, Duret C, Le Goupil S, Laprade H, Martin S, Brugière S, Couté Y, Machon C, Guitton J, et al.Tyr1148 (4404; 1:1,000), p-Shc Tyr239/240 (2434; 1:1,000), p-Gab1 Tyr627 (3233; 1:1,000), p-PLCg1 Tyr783 (2821; 1:1,000), p-ERK (4370; 1:1,000), β-Tubulin (2146; 1:1,000), actin (8432; 1/1,000), PD-L1 (13684; 1:1,000),

(11) Characterization of KRC-108 as a TrkA Kinase Inhibitor with Anti-Tumor EffectsBiomolecules & TherapeuticsJuly 1, 2022Hyo Jeong Lee, Yeongyu Moon, Jungil Choi, Jeong Doo Heo, Sekwang Kim, Hari Krishna Nallapaneni, Young-Won Chin, Jongkook Lee, Sun-Young Hanphospho-Akt (Ser473; #9271; 1:1000), phospho-p44/42 MAPK (ERK1/2; #4370; 1:1000), phospho-PLCγ1 (Tyr783; #2821; 1:1000), PARP (#9542; 1:1000), and LC3A/B (D3U4C; #12741; 1:1000) were purchased from Cell Signaling Technology

(12) Cholenic acid derivative UniPR1331 impairs tumor angiogenesis via blockade of VEGF/VEGFR2 in addition to Eph/ephrinCancer Gene TherapyJuly 1, 2022Marco Rusnati et al.by western blot for the phosphorylated form of VEGFR2, ERK1/2 (#4370, Cell Signalling), or PLC-γ (#2821, Cell Signalling). For FGFR1 phosphorylation assay, cells were treated as above with FGF2 at 30 ng/ml. VEGFR2

(13) NK Cells Equipped With a Chimeric Antigen Receptor That Overcomes Inhibition by HLA Class I for Adoptive Transfer of CAR-NK CellsFrontiers in ImmunologyMay 2, 2022Xiaoxuan Zhuang, Eric O. Longanalyzing by western blot using phospho-Erk1/2 (Cell Signaling #9101) and phospho-PLCγ1 (Cell Signaling #2821) antibodies. Data Sharing Statement All supporting data are available on request. Results Synergistic

(14) NAD⁺-boosting molecules suppress mast cell degranulation and anaphylactic responses in miceTheranosticsApril 11, 2022Hyun-Woo Kim, Ga-Hee Ryoo, Hyun-Young Jang, So-Young Rah, Dong Hyun Lee, Do-Kyun Kim, Eun Ju Bae, Byung-Hyun ParkAbcam), LAT (sc-53550, Santa Cruz Biotechnology), Sirt6 (#12486), p-Syk (#2717), Syk (#13198), p-PLCγ (#2821), p-PI3K (#4228), PI3K (#4257), p-Akt (#9271), Akt (#9272), p-ERK (#4370), ERK (#9102), p-p38 (#9211),

(15) FGFR3 overactivation in the brain is responsible for memory impairments in Crouzon syndrome mouse modelThe Journal of experimental medicineApril 4, 2022Cornille M, Moriceau S, Khonsari RH, Heuzé Y, Loisay L, Boitez V, Morice A, Arnaud E, Collet C, Bensidhoum M, et al.number 9411; 1:1,000 dilution; Cell Signaling), a polyclonal anti-phospho-PLCγ1 antibody (catalog number 2821; 1:1,000 dilution; Cell Signaling), a polyclonal anti-PLCγ1 antibody (catalog number 2822; 1:1,000 dilution;

(16) Coronin 1A facilitates calcium mobilization and promotes astrocyte reactivity in HIV‐1 neuropathogenesisFASEB BioAdvancesApril 1, 2022Hriday Shanker Pandey, Rishabh Kapoor, Bindu, Pankaj Seth(Cell Signaling Technology, 1:2000, Cat# 9102S), rabbit anti‐Phospho‐PLCγ1 (Cell signaling, 1:1000, Cat# 2821S, RRID:AB_330855), rabbit anti‐PLCγ1 (Cell signaling, 1:1000, Cat# 2822S, RRID:AB_2163702), rabbit anti‐GFAP

(17) Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated stateMolecular CellMarch 17, 2022Chi-Chuan Lin et al.ab107455; RRID:AB_11156766 Anti-Phospho-PLCγ1 (Tyr783) Rabbit Polyclonal,Cell Signaling Technology,Cat#: 2821; RRID:AB_330855 "Anti-PLCγ1 Rabbit Polyclonal, KO validated",Cell Signaling Technology,Cat#: 2822;

(18) Inhibition of SHP-1 activity by PKC-Î¸ regulates NK cell activation threshold and cytotoxicityeLifeMarch 8, 2022Aviad Ben-Shmuel, Batel Sabag, Abhishek Puthenveetil, Guy Biber, Moria Levy, Tammir Jubany, Fatima Awwad, Roshan Kumar Roy, Noah Joseph, Omri Matalon, et al.1:1000 (7 µL)IF: 1:500 (0.6 µL) Antibody,Anti-human pPLCγ (Y783) (rabbit polyclonal),Cell Signaling,CST-2821S,IB: 1:1000 (7 µL)IF: 1:500 (0.6 µL) Antibody,Anti-human pVAV1 (Y160) (rabbit polyclonal),Bio Source,Bs-44482,IB:

(19) In vitro reconstitution reveals cooperative mechanisms of adapter protein-mediated activation of phospholipase C-Î³1 in T cellsJournal of Biological ChemistryMarch 1, 2022Junya Wada, Udumbara Rathnayake, Lisa M. Jenkins, Avinash Singh, Moosa Mohammadi, Ettore Appella, Paul A. Randazzo, Lawrence E. Samelsonthe degree of phosphorylation of PLC-γ1 at Tyr783 was measured by Western blot using anti-pPLC-γ1 (#2821, Cell Signaling) and detected with anti-rabbit IgG-HRP (NXA934, Amersham GE)]. The chemiluminescent

(20) Deubiquitinating enzymes USP4 and USP17 finetune the trafficking of PDGFRβ and affect PDGF-BB-induced STAT3 signallingCellular and Molecular Life SciencesFebruary 1, 2022Niki Sarri, Kehuan Wang, Maria Tsioumpekou, Casimiro Castillejo-López, Johan Lennartsson, Carl-Henrik Heldin, Natalia Papadopoulosphosphorylated p44/p42 MAPK (pErk1/2, pThr202/pThr204, #9101), PLCγ1 (#2822), phosphorylated PLCγ1 (pTyr783, #2821), STAT3 (79D7, #4904) and phosphorylated STAT3 (pTyr705, D3A7, #9145) were purchased from Cell Signalling

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(1)

6/23/2020Good Antibody for Phospho-PLCgamma1 from CST Hong SunMight need to titrate before use.
(1)

8/21/2015Time Course Effect of Chemotactic Agent on Phospho-PLC-gamma-1 in HASMS Somasundaram RaghavanPhosphoinositide-specific phospholipase C (PLC) is a receptor of the tyrosine kinase family which is activated upon various stimuli like growth factors and hormones. Phosphorylation at Tyr783 is one ... Read Review
(1)

8/14/2015Good Phospho-PLC-gamma-1 Antibody Raj KumarIn present experiment, equal amount of proteins from growth factor treated cells were resolved in 7.5% SDS-PAGE. Western transfer was done in nitrocellulose membrane and immunodetection was done for ... Read Review

Phospho-PLCgamma1 (Tyr783) Antibody

Phospho-PLCgamma1 (Tyr783) Antibody from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-PLCgamma1 (Tyr783) Antibody from Cell Signaling Technology

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