PXR Antibody from BioLegend

PXR Antibody from BioLegend

BioLegend's PXR Antibody is a Rabbit Polyclonal antibody. The PXR Antibody was generated using PXR, PAR2, PRR, nuclear receptor subfamily 1, group I, member 2, SXR, ONR1, SAR, PARq, BXR, NR1I2, PAR, PAR1 as the antigen and it reacts with Mouse, Human. This antibody has been shown to work in applications such as: Western Blot.

Description

Purified anti-PXR [Poly6169]

Specifications

  • Detailed Specifications
  • ItemPXR Antibody
  • CompanyBioLegend
  • Price Pricing InfoSupplier PageView Company Product Page
  • Catalog Number616901
  • Quantity50 µl
  • ApplicationsWB
  • Conjugate/Tag/LabelUnconjugated
  • FormatThis antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 50% glycerol
  • ReactivityHuman, Mouse
  • AntigenPXR
  • ClonePoly6169
  • HostRabbit
  • Primary / SecondaryPrimary
  • ImmunogenRecombinant (partial), N-terminal
  • NCBI Full Gene Namenuclear receptor subfamily 1, group I, member 2
  • NCBI Gene AliasesBXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR
  • ClonalityPolyclonal

References

Chen Y, Tang Y, Wang MT, Zeng S, Nie D. Human pregnane X receptor and resistance to chemotherapy in prostate cancer. Cancer Res. 2007 Nov 1;67(21):10361-7.

Gupta D, Venkatesh M, Wang H, Kim S, Sinz M, Goldberg GL, Whitney K, Longley C, Mani S. Expanding the roles for pregnane X receptor in cancer: proliferation and drug resistance in ovarian cancer. Clin Cancer Res. 2008 Sep 1;14(17):5332-40.

Hartz AM, Miller DS, Bauer B. Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease. Mol Pharmacol. 2010 May;77(5):715-23.

Wang H, Li H, Moore LB, Johnson MD, Maglich JM, Goodwin B, Ittoop OR, Wisely B, Creech K, Parks DJ et al. The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor. Mol Endocrinol. 2008 Apr;22(4):838-57.
BioLegend
BioLegend
9727 Pacific Heights Blvd
San Diego, California 92121
United States
Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Citations