PXR Antibody from BioLegend

PXR Antibody from BioLegend

The PXR Antibody from BioLegend is a Rabbit Polyclonal antibody to PXR, PAR2, PRR, nuclear receptor subfamily 1, group I, member 2, SXR, ONR1, SAR, PARq, BXR, NR1I2, PAR, PAR1. This antibody recognizes Mouse, Human antigen. The PXR Antibody has been validated for the following applications: Western Blot.

Description

Purified anti-PXR [Poly6169]

Specifications

  • Detailed Specifications
  • ItemPXR Antibody
  • CompanyBioLegend
  • Price Pricing InfoSupplier PageView Company Product Page
  • Catalog Number616901
  • Quantity50 µl
  • ApplicationsWB
  • Conjugate/Tag/LabelUnconjugated
  • FormatThis antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 50% glycerol
  • ReactivityHuman, Mouse
  • AntigenPXR
  • ClonePoly6169
  • HostRabbit
  • Primary / SecondaryPrimary
  • ImmunogenRecombinant (partial), N-terminal
  • NCBI Full Gene Namenuclear receptor subfamily 1, group I, member 2
  • NCBI Gene AliasesBXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR
  • ClonalityPolyclonal

References

Chen Y, Tang Y, Wang MT, Zeng S, Nie D. Human pregnane X receptor and resistance to chemotherapy in prostate cancer. Cancer Res. 2007 Nov 1;67(21):10361-7.

Gupta D, Venkatesh M, Wang H, Kim S, Sinz M, Goldberg GL, Whitney K, Longley C, Mani S. Expanding the roles for pregnane X receptor in cancer: proliferation and drug resistance in ovarian cancer. Clin Cancer Res. 2008 Sep 1;14(17):5332-40.

Hartz AM, Miller DS, Bauer B. Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease. Mol Pharmacol. 2010 May;77(5):715-23.

Wang H, Li H, Moore LB, Johnson MD, Maglich JM, Goodwin B, Ittoop OR, Wisely B, Creech K, Parks DJ et al. The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor. Mol Endocrinol. 2008 Apr;22(4):838-57.
BioLegend
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