- Anti-PXR
- BioLegend
- Pricing InfoSupplier PageView Company Product Page
- 616901
- 50 µl
- WB
- Unconjugated
- This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 50% glycerol
- Human, Mouse
- PXR
- Poly6169
- Rabbit
- (Poly6169)
- Orphan nuclear receptor PXR, Pregnane X receptor, Orphan nuclear receptor PAR1, Steroid and xenobiotic receptor (SXR)
- Primary
- nuclear receptor subfamily 1, group I, member 2
- Recombinant (partial), N-terminal
- nuclear receptor subfamily 1, group I, member 2
- BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR
- Polyclonal
Product Description
Purified anti-PXR
References
Chen Y, Tang Y, Wang MT, Zeng S, Nie D. Human pregnane X receptor and resistance to chemotherapy in prostate cancer. Cancer Res. 2007 Nov 1;67(21):10361-7.
Gupta D, Venkatesh M, Wang H, Kim S, Sinz M, Goldberg GL, Whitney K, Longley C, Mani S. Expanding the roles for pregnane X receptor in cancer: proliferation and drug resistance in ovarian cancer. Clin Cancer Res. 2008 Sep 1;14(17):5332-40.
Hartz AM, Miller DS, Bauer B. Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease. Mol Pharmacol. 2010 May;77(5):715-23.
Wang H, Li H, Moore LB, Johnson MD, Maglich JM, Goodwin B, Ittoop OR, Wisely B, Creech K, Parks DJ et al. The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor. Mol Endocrinol. 2008 Apr;22(4):838-57.