The MACSQuant® Tyto® Cell Sorter brings a gentler, safer, and sterile flow sorting technology to your lab. With the microchip technology at its heart, cells will no longer be exposed to electrical charge, decompression, and fluidic systems. Instead, cells are sorted within a single-use, sterile, and closed cartridge, providing full safety for operators.
The MACSQuant Tyto is equipped with three lasers, which allows cell sorting with up to 10 parameters. The easy “plug and play” format of the instrument and the cartridge, combined with fully automated flow control, laser alignment, and valve timing, makes cell sorting accessible to any lab professional, without intensive training.
Features & benefits:
- Microchip technology enables gentler cell sorting
- Closed, single-use cartridge provides operator safety and prevents sample contamination
- Three lasers (405 nm, 488 nm, 638 nm), eight fluorescence channels, plus two scatter channels allow sorting with up to 10 parameters
Since the actual sorting process takes place completely within the Tyto Cartridge, there is no risk of losing precious sample material and therefore the sorting process is entirely operator-free. With its extremely compact design, the MACSQuant Tyto is a true benchtop instrument that perfectly fits into a typical lab environment.
The heart of the system is the MACSQuant Tyto Cartridge, a single-use disposable carrying the actual sorting microchip. Unlike in conventional droplet sorters, no fluidic tubing is present in the instrument itself. Additionally, cells sorted by the MACSQuant Tyto do not experience high sorting pressure, charge, or decompression. Instead, a very mild and constant filtered air pressure (< 3 psi) drives the cells through the microchip for sorting, and subsequently either into the positive or negative collection chamber (two-way sorting). The lack of fluidic tubing in the system means that fluidics start-up and laborious cleaning procedures are no longer required, saving operator-time and reducing costs. Furthermore, sorting temperature can be cooled down to 4 °C, providing optimal conditions to retain highest cell viabilities and functionalities.
Miltenyi Biotec offers three different cartridges to perfectly meet your experimental needs. The MACSQuant Tyto Cartridge is your choice to sort fragile cells with a flow rate of up to 55,000 cells/second and 30,000 valve actuations/second. The MACSQuant Tyto Cartridge HS has been specifically designed to facilitate never-before-seen high-speed cell sorting at a doubled flow rate (up to 110,000 cells/second). Furthermore, the MACS GMP Tyto Cartridge was specifically designed to facilitate the translation of multiparameter cell sorting protocols into clinics, including an extensive amount of documentation and regulatory support (CoA, CoO, and PIF).
The MACSQuant Tyto standard equipment includes an external 32-inch monitor for convenient data analysis. At the click of a button, you’ll have worldwide 24-hour remote support. Our live support service allows users to interact directly with MACSQuant Application Specialists in real time. Your dedicated support specialist can review your software setup and take control over the instrument to resolve any issues if desired.